|
Клеточные линии/сравнение результатов эксперимента |
Коэффициент корреляции Пирсона |
|
|
BJa и BJb |
0.993192843 |
|
|
BJa и BJc |
0.989497022 |
|
|
BJb и BJc |
0.985813875 |
|
|
HUES6a и HUES6b |
0.995517397 |
|
|
HUES6a и HUES6c |
0.993074263 |
|
|
HUES6b и HUES6c |
0.993994747 |
|
|
Гибрид1a и Гибрид1b |
0.988061956 |
|
|
Гибрид1a и Гибрид1c |
0.988676815 |
|
|
Гибрид1b и Гибрид1c |
0.997182504 |
|
|
Гибрид2a и Гибрид2b |
0.988584931 |
|
|
Гибрид2a и Гибрид2c |
0.989424668 |
|
|
Гибрид2b и Гибрид2c |
0.995896499 |
|
|
BJa и HUES6a |
0.780113998 |
|
|
BJa и HUES6b |
0.783036581 |
|
|
BJa и HUES6c |
0.777684475 |
|
|
BJb и HUES6a |
0.775574204 |
|
|
BJb и HUES6b |
0.777159461 |
|
|
BJb и HUES6c |
0.768892567 |
|
|
BJc и HUES6a |
0.788160554 |
|
|
BJc и HUES6b |
0.783330285 |
|
|
BJc и HUES6c |
0.789551854 |
|
|
HUES6a и Гибрид1a |
0.985106622 |
|
|
HUES6a и Гибрид1b |
0.987711238 |
|
|
HUES6a и Гибрид1c |
0.987835323 |
|
|
HUES6b и Гибрид1a |
0.986198747 |
|
|
HUES6b и Гибрид1b |
0.987454291 |
|
|
HUES6b и Гибрид1c |
0.989156158 |
|
|
HUES6c и Гибрид1a |
0.979331587 |
|
|
HUES6c и Гибрид1b |
0.980132796 |
|
|
HUES6c и Гибрид1c |
0.983813233 |
|
|
HUES6a и Гибрид2a |
0.985215616 |
|
|
HUES6a и Гибрид2b |
0.983615228 |
|
|
HUES6a и Гибрид2c |
0.988515551 |
|
|
HUES6b и Гибрид2a |
0.985814214 |
|
|
HUES6b и Гибрид2b |
0.983742876 |
|
|
HUES6b и Гибрид2c |
0.989432206 |
|
|
HUES6c и Гибрид2a |
0.980753157 |
|
|
HUES6c и Гибрид2b |
0.978194057 |
|
|
HUES6c и Гибрид2c |
0.98447334 |
|
|
BJa и Гибрид1a |
0.790637823 |
|
|
BJa и Гибрид1b |
0.79328967 |
|
|
BJa и Гибрид1c |
0.79715334 |
|
|
BJb и Гибрид1a |
0.788816206 |
|
|
BJb и Гибрид1b |
0.791418124 |
|
|
BJb и Гибрид1c |
0.793628529 |
|
|
BJc и Гибрид1a |
0.79413977 |
|
|
BJc и Гибрид1b |
0.799152853 |
|
|
BJc и Гибрид1c |
0.801022877 |
|
|
BJa и Гибрид2a |
0.785943279 |
|
|
BJa и Гибрид2b |
0.795160469 |
|
|
BJa и Гибрид2c |
0.796298791 |
|
|
BJb и Гибрид2a |
0.783867626 |
|
|
BJb и Гибрид2b |
0.794416133 |
|
|
BJb и Гибрид2c |
0.793826462 |
|
|
BJc и Гибрид2a |
0.788075491 |
|
|
BJc и Гибрид2b |
0.794183407 |
|
|
BJc и Гибрид2c |
0.799337756 |
|
|
HUES1a и H2b* |
0.984479464 |
|
|
HUES1a и H2c* |
0.976024017 |
|
|
HUES1b и H2c* |
0.989124914 |
|
|
HUES1a и H2b* |
0.986568582 |
|
|
HUES1a и H2c* |
0.942357736 |
|
|
HUES1b и H2c* |
0.974081347 |
|
|
HUES1a и H2a* |
0.97814981 |
|
|
HUES1a и H2b* |
0.970728278 |
|
|
HUES1a и H2c* |
0.942003485 |
|
|
HUES1b и H2a* |
0.973740557 |
|
|
HUES1b и H2b* |
0.950496363 |
|
|
HUES1b и H2c* |
0.89679701 |
|
|
HUES1c и H2a* |
0.969536314 |
|
|
HUES1c и H2b* |
0.941426819 |
|
|
HUES1c и H2c* |
0.887338919 |
|
|
HSF-6b и HSF-6c** |
0.9963 |
|
|
HSF-6b и HSF-1b** |
0.9728 |
|
*Cowan и Melton, неопубликованные данные, по оценке свыше 22284 наборов проб.
**( M.J. Abeyta et al, Hum Mol Genet. 13, 601 (2004).)
|
Название гена |
Хр. |
Номер |
Связан с локусом |
Среднее изменение в гибридных клетках по сравнению с HUES6 |
Среднее изменение в BJ клетках по сравнению с HUES6 |
|
Hypothetical protein LOC205251 |
2 |
AW182614 |
205251 |
7.86 |
25.84 |
|
Insulin-like growth factor binding protein 5 |
2 |
R73554 |
3488 |
6.82 |
122.61 |
|
Insulin-like growth factor binding protein 5 |
2 |
AW007532 |
3488 |
3.24 |
22.02 |
|
Insulin-like growth factor binding protein 5 |
2 |
BM128432 |
3488 |
2.86 |
24.12 |
|
Phosphoserine phosphatase |
7 |
NM 003832 |
5723 |
111 |
3.84 |
|
Similar to RIKEN cDNA2610524G09 |
9 |
AL555612 |
389792 |
3.13 |
5.58 |
|
Glutathione S-transferase theta 1 |
22 |
NM 000853 |
2952 |
21.45 |
47.22 |
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 |
Y |
NM 004660 |
8653 |
22.41 |
22.53 |
|
Jumonji, AT rich interactive domain 1D |
Y |
NM 004653 |
8284 |
8.55 |
9.88 |
|
Ubiquitin specific protease 9 |
Y |
AV681765 |
8287 |
5.58 |
5.84 |
|
Eukaryotic translation initiation factor 1A |
Y |
BC005248 |
9086 |
5.39 |
3.57 |
|
Ribosomal protein S4 |
Y |
NM 001008 |
6192 |
4.08 |
5.71 |
|
Название гена |
Хр. |
Номер |
Связан с локусом |
Среднее изменение в гибридных клетках по сравнению с HUES6 |
Среднее изменение в BJ клетках по сравнению с HUES6 |
|
Hypothetical protein FLJ40434 |
1 |
AI223281 |
163742 |
-3.38 |
-53.74 |
|
RAP1 A, member of RAS oncogene family |
1 |
AB051846 |
5906 |
-2.77 |
-20.35 |
|
RAP1 A, member of RAS oncogene family |
1 |
AB051846 |
5906 |
-2.44 |
-125.27 |
|
Major histocompatibility complex, class II, DQ |
6 |
AI583173 |
3119 |
-9.18 |
-700 |
|
beta 1 |
|
|
|
|
|
|
Major histocompatibility complex, class II, DQ |
6 |
AW276186 |
3119 |
-8.26 |
-1267.77 |
|
beta 1 |
|
|
|
|
|
|
Major histocompatibility complex, class II, DQ |
6 |
M16276 |
3119 |
-6.91 |
-17.56 |
|
beta 1 |
|
|
|
|
|
|
Major histocompatibility complex, class II, DQ |
6 |
M17565 |
3119 |
-4.49 |
-59.98 |
|
beta 1 |
|
|
|
|
|
|
Major histocompatibility complex, class II, DQ |
6 |
M32577 |
3119 |
-4.28 |
-931.28 |
|
beta1 |
|
|
|
|
|
|
Major histocompatibility complex, class II, DQ |
6 |
M17955 |
3119 |
-2.98 |
-764.84 |
|
beta1 |
|
|
|
|
|
|
Embryonal stem cell specific gene 1 |
6 |
AI365263 |
340168 |
-3.6 |
-475.13 |
|
Chromosome 6 ORF 62 |
6 |
AW972292 |
- |
-2.3 |
-2.82 |
|
Similar to DKFZP566O084 protein |
17 |
AI741629 |
201140 |
-4.33 |
-12.84 |
|
(LOC201140), mRNA |
|
|
|
|
|
|
Polymerase (DNA directed), gamma 2, |
17 |
NM_007215 |
11232 |
-3.28 |
-12.78 |
|
accessory subunit |
|
|
|
|
|
|
Paternally expressed 3 |
19 |
AL042588 |
5178 |
-11.89 |
-15.53 |
|
Chromosome 20 ORF 54 |
20 |
AA903862 |
113278 |
-4.38 |
-255.1 |
|
DNA (cytosine-5-)-methyltransferase 3-like |
21 |
NM 013369 |
29947 |
-5.52 |
-572.59 |
|
Apolipoprotein B mRNA editing enzyme, |
22 |
NM_004900 |
9582 |
-2.9 |
-3.56 |
|
catalytic polypeptide-like 3B |
|
|
|
|
|
|
Glutathione S-transferase theta 2 |
22 |
NM 000854 |
2953 |
-2.48 |
-7.5 |
|
Monoamine oxidase A |
X |
NM 000240 |
4128 |
-3.05 |
-9.15 |
|
CDNA clone IMAGE:6101827, partial cds |
X |
AK026566 |
203413 |
-2.28 |
-12.13 |
|
Ген |
Хр. |
Связан с локусом |
Среднее изменение в HUES6 по сравнению с BJ |
Среднее изменение в гибридных клетках по сравнению с BJ |
|
SRY (sex determining region Y)-box 2 (SOX2) |
3 |
6657 |
561.51 |
616.34 |
|
Teratocarcinoma-derived growth factor 1 (TDGF1) |
3 |
6997 |
320.42 |
323.82 |
|
Developmental pluripotency associated 4 (DPPA4) |
3 |
55211 |
106.42 |
105.15 |
|
Zinc finger protein 42 (REX1) |
4 |
132625 |
34.38 |
27.15 |
|
POU domain, class 5, transcription factor 1 (OCT4) |
6 |
5460 |
6099.75 |
5963.07 |
|
Undifferentiated embryonic cell transcription factor 1(UTF1) |
10 |
8433 |
25.8 |
22.04 |
|
Nanog |
12 |
79923 |
3662.53 |
3403.35 |
|
Bone morphogenetic protein 2 (BMP2) |
20 |
650 |
1251.4 |
1546.19 |